The cloning of human Smac gene and its pro-apoptotic effect on Burkitt's lymphoma cells
OBJECTIVE: Second mitochondria-derived activator of caspase (Smac) is a recently identified, novel pro-apoptotic molecule, which is released from mitochondria into the cytosol during apoptosis. Smac promotes activation of caspases by neutralizing members of the inhibitor of apoptosis proteins (IAPs)...
Publié dans: | Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 43(2005), 7 vom: 08. Juli, Seite 503-6 |
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Auteur principal: | |
Autres auteurs: | , , , , , , , , , |
Format: | Article |
Langue: | Chinese |
Publié: |
2005
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Accès à la collection: | Zhonghua er ke za zhi = Chinese journal of pediatrics |
Sujets: | Journal Article Research Support, Non-U.S. Gov't Apoptosis Regulatory Proteins DIABLO protein, human DNA, Complementary Intracellular Signaling Peptides and Proteins Mitochondrial Proteins Caspase 3 EC 3.4.22.- |