The cloning of human Smac gene and its pro-apoptotic effect on Burkitt's lymphoma cells

OBJECTIVE: Second mitochondria-derived activator of caspase (Smac) is a recently identified, novel pro-apoptotic molecule, which is released from mitochondria into the cytosol during apoptosis. Smac promotes activation of caspases by neutralizing members of the inhibitor of apoptosis proteins (IAPs)...

Description complète

Détails bibliographiques
Publié dans:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 43(2005), 7 vom: 08. Juli, Seite 503-6
Auteur principal: Lu, Chao (Auteur)
Autres auteurs: Wu, Sheng-hua, Chen, Ji-qing, Zhao, Fei, Chi, Xia, Pan, Xiao-qin, Fei, Li, Guo, Mei, Huang, Song-ming, Guo, Xi-rong, Chen, Rong-hua
Format: Article
Langue:Chinese
Publié: 2005
Accès à la collection:Zhonghua er ke za zhi = Chinese journal of pediatrics
Sujets:Journal Article Research Support, Non-U.S. Gov't Apoptosis Regulatory Proteins DIABLO protein, human DNA, Complementary Intracellular Signaling Peptides and Proteins Mitochondrial Proteins Caspase 3 EC 3.4.22.-