The cloning of human Smac gene and its pro-apoptotic effect on Burkitt's lymphoma cells

The cloning of human Smac gene and its pro-apoptotic effect on Burkitt's lymphoma cells

OBJECTIVE: Second mitochondria-derived activator of caspase (Smac) is a recently identified, novel pro-apoptotic molecule, which is released from mitochondria into the cytosol during apoptosis. Smac promotes activation of caspases by neutralizing members of the inhibitor of apoptosis proteins (IAPs)...

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Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 43(2005), 7 vom: 08. Juli, Seite 503-6
1. Verfasser: Lu, Chao (VerfasserIn)
Weitere Verfasser: Wu, Sheng-hua, Chen, Ji-qing, Zhao, Fei, Chi, Xia, Pan, Xiao-qin, Fei, Li, Guo, Mei, Huang, Song-ming, Guo, Xi-rong, Chen, Rong-hua
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Apoptosis Regulatory Proteins DIABLO protein, human DNA, Complementary Intracellular Signaling Peptides and Proteins Mitochondrial Proteins Caspase 3 EC 3.4.22.-