Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers

Delivery of phosphorodiamidate morpholino oligomers (PMO) into fish cells in vitro and tissues in vivo was examined. Uptake was evaluated by fluorescence microscopy and flow cytometry after treating cultured cells or live rainbow trout with 3' fluorescein-tagged PMO. Arginine-rich peptide conju...

Description complète

Détails bibliographiques
Publié dans:Journal of fish diseases. - 1998. - 28(2005), 7 vom: 15. Juli, Seite 399-410
Auteur principal: Alonso, M (Auteur)
Autres auteurs: Stein, D A, Thomann, E, Moulton, H M, Leong, J C, Iversen, P, Mourich, D V
Format: Article
Langue:English
Publié: 2005
Accès à la collection:Journal of fish diseases
Sujets:Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Antiviral Agents Morpholines Morpholinos Peptides RNA, Viral