Factors affecting double-strand break-induced homologous recombination in mammalian cells

Double-strand break (DSB)-induced homologous recombination (HR) of direct repeats is a powerful means to achieve gene excision, a critical step in genome engineering. In this report we have used an extrachrmosomal reporter system to monitor the impact of different parameters on meganuclease-induced...

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Détails bibliographiques
Publié dans:BioTechniques. - 1991. - 39(2005), 1 vom: 30. Juli, Seite 109-15
Auteur principal: Perez, Christophe (Auteur)
Autres auteurs: Guyot, Valérie, Cabaniols, Jean-Pierre, Gouble, Agnès, Micheaux, Beatrice, Smith, Julie, Leduc, Sophie, Pâques, Frédéric, Duchateau, Philippe
Format: Article
Langue:English
Publié: 2005
Accès à la collection:BioTechniques
Sujets:Journal Article DNA, Single-Stranded