Surface-induced aggregation of beta amyloid peptide by co-substituted alkanethiol monolayers supported on gold

The primary pathological characteristic of Alzheimer's disease is the presence in the brain of self-assembled beta amyloid (Abeta) protein fibrils, consisting of 35-43 amino acid residues. The toxicity of the aggregated protein structures has previously been proposed to be related to the intera...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 21(2005), 10 vom: 10. Mai, Seite 4464-70
Auteur principal: McMasters, Mariah J (Auteur)
Autres auteurs: Hammer, Robert P, McCarley, Robin L
Format: Article
Langue:English
Publié: 2005
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Alkanes Amyloid beta-Peptides Multiprotein Complexes Sulfhydryl Compounds Gold 7440-57-5