Structure of polypeptide-based diblock copolymers in solution : stimuli-responsive vesicles and micelles

Polypeptide-based diblock copolymers forming either well-defined self-assembled micelles or vesicles after direct dissolution in water or in dichloromethane have been studied combining light and neutron scattering with electron microscopy experiments. The size of these structures could be reversibly...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 21(2005), 10 vom: 10. Mai, Seite 4308-15
1. Verfasser: Chécot, Frédéric (VerfasserIn)
Weitere Verfasser: Brûlet, Annie, Oberdisse, Julian, Gnanou, Yves, Mondain-Monval, Olivier, Lecommandoux, Sébastien
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Biopolymers Micelles Peptides Solutions
Beschreibung
Zusammenfassung:Polypeptide-based diblock copolymers forming either well-defined self-assembled micelles or vesicles after direct dissolution in water or in dichloromethane have been studied combining light and neutron scattering with electron microscopy experiments. The size of these structures could be reversibly manipulated as a function of environmental changes such as pH and ionic strength in water. Compared to other pH-responsive self-assembled systems based on "classical" polyelectrolytes, these polypeptide-based nanostructures present the ability to give a response in highly salted media as the chain conformational ordering can be controlled. This makes these micelles and vesicles suitable for biological applications: they provide significant advantages in the control of the structure and function of supramolecular self-assemblies
Beschreibung:Date Completed 23.06.2006
Date Revised 26.10.2019
published: Print
Citation Status MEDLINE
ISSN:1520-5827