Impaired cytolytic activity in peripheral blood T cells from renal cell carcinoma patients

Impaired cytolytic activity in peripheral blood T cells from renal cell carcinoma patients

Classic T lymphocyte cytotoxicity is mediated through the T cell receptor (TCR). Defects in TCR signal transduction and cytolytic activity have been reported in tumor infiltrating T lymphocytes. We hypothesized that impaired cytotoxicity occurs in peripheral blood T cells from renal cell carcinoma (...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 117(2005), 1 vom: 01. Okt., Seite 6-11
1. Verfasser: Crocenzi, Todd S (VerfasserIn)
Weitere Verfasser: Tretter, Christopher P G, Schwaab, Thomas, Schned, Alan R, Heaney, John A, Cole, Bernard F, Fisher, Jan L, Ernstoff, Marc S
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. CD3 Complex CD8 Antigens Interleukin-2 Receptors, Antigen, T-Cell Recombinant Proteins