Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages

Cyclophilin A may contribute to the inflammatory processes in rheumatoid arthritis through induction of matrix degrading enzymes and inflammatory cytokines from macrophages

Cyclophilin A (CypA) levels increase in the sera and synovial fluids of rheumatoid arthritis (RA) patients, but the cell types expressing CypA and the function of CypA in the pathogenesis of RA are not known yet. Immunohistochemistry analyses revealed high level CypA staining in the macrophages in t...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 116(2005), 3 vom: 01. Sept., Seite 217-24
1. Verfasser: Kim, Ho (VerfasserIn)
Weitere Verfasser: Kim, Won-Jung, Jeon, Sung-Tak, Koh, Eun-Mi, Cha, Hoon-Suk, Ahn, Kwang-Sung, Lee, Won-Ha
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Cytokines Inflammation Mediators Matrix Metalloproteinase 9 EC 3.4.24.35 Cyclophilin A EC 5.2.1.-