Complex formation between cationically modified gold nanoparticles and DNA : an atomic force microscopic study

Atomic force microscopy has been used for direct visualization of the wrapping of DNA around 30-nm-sized functionalized gold nanoparticles for the first time. The morphology of the complexes seems to be dictated by the relative concentration of the nanoparticles and DNA. A higher concentration of th...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 20(2004), 13 vom: 22. Juni, Seite 5165-70
1. Verfasser: Ganguli, Munia (VerfasserIn)
Weitere Verfasser: Babu, J Venkatesh, Maiti, Souvik
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Letter Cations Gold 7440-57-5 DNA 9007-49-2
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520 |a Atomic force microscopy has been used for direct visualization of the wrapping of DNA around 30-nm-sized functionalized gold nanoparticles for the first time. The morphology of the complexes seems to be dictated by the relative concentration of the nanoparticles and DNA. A higher concentration of the former leads to the formation of a network of nanoparticles assembled on DNA. This assembly pattern seems to be significantly different from the manner in which cationically modified gold nanoparticles of smaller size (< 5 nm) arrange linearly on DNA, as shown in the literature. A DNA-gold nanoparticle can be developed as a model system for in vitro studies on the mechanism of DNA condensation and also for developing novel methods of nanoparticle self-assembly on the DNA template 
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700 1 |a Maiti, Souvik  |e verfasserin  |4 aut 
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