CpG oligodeoxynucleotides stimulate cord blood mononuclear cells to produce immunoglobulins
CpG oligodeoxynucleotides (ODNs) stimulate adult B cells leading to cellular proliferation and immunoglobulin production. It is unknown if CpG-ODNs similarly stimulate neonatal human B cells. Neonates have immature immune responses and are poorly responsive to thymus independent antigens such as pol...
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 116(2005), 3 vom: 15. Sept., Seite 236-45 |
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| Format: | Article |
| Langue: | English |
| Publié: |
2005
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| Accès à la collection: | Clinical immunology (Orlando, Fla.) |
| Sujets: | Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Adjuvants, Immunologic Antibodies, Bacterial CPG-oligonucleotide Immunoglobulins Oligodeoxyribonucleotides Pneumococcal Vaccines |