CpG oligodeoxynucleotides stimulate cord blood mononuclear cells to produce immunoglobulins

CpG oligodeoxynucleotides (ODNs) stimulate adult B cells leading to cellular proliferation and immunoglobulin production. It is unknown if CpG-ODNs similarly stimulate neonatal human B cells. Neonates have immature immune responses and are poorly responsive to thymus independent antigens such as pol...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 116(2005), 3 vom: 15. Sept., Seite 236-45
1. Verfasser:	Landers, Cheri D (VerfasserIn)
Weitere Verfasser:	Bondada, Subbarao
Format:	Aufsatz
Sprache:	English
Veröffentlicht:	2005
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Adjuvants, Immunologic Antibodies, Bacterial CPG-oligonucleotide Immunoglobulins Oligodeoxyribonucleotides Pneumococcal Vaccines Polysaccharides, Bacterial