Cationic DMPC/DMTAP lipid bilayers : local lateral polarization of phosphatidylcholine headgroups
We investigated the effect of dimyristoyltrimethylammonium propane (DMTAP) charge on area per molecule of mixed DMTAP/dimyristoylphosphatidylcholine (DMPC) bilayers in a simple model. Assuming that trimethylammonium (TAP) charge causes lateral polarization of neighboring PC molecules, we analyzed va...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1991. - 21(2005), 13 vom: 21. Juni, Seite 5677-80 |
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| Format: | Aufsatz |
| Sprache: | English |
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2005
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Cations Lipid Bilayers Phosphatidylcholines Dimyristoylphosphatidylcholine U86ZGC74V5 |
| Zusammenfassung: | We investigated the effect of dimyristoyltrimethylammonium propane (DMTAP) charge on area per molecule of mixed DMTAP/dimyristoylphosphatidylcholine (DMPC) bilayers in a simple model. Assuming that trimethylammonium (TAP) charge causes lateral polarization of neighboring PC molecules, we analyzed variation in area per molecule as the mole fraction of TAP increases. The theoretical predictions obtained in the present study are consistent with results of a recent molecular dynamics simulation study (Gurtovenko et al. Biophys. J. 2004, 86, 3461) |
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| Beschreibung: | Date Completed 23.06.2006 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
| ISSN: | 0743-7463 |