Role of intramolecular epitope spreading in pemphigus vulgaris

Role of intramolecular epitope spreading in pemphigus vulgaris

Pemphigus vulgaris (PV) is an acquired immunobullous disorder. At the early stage of the disease (mucosal PV), patients display only autoimmunity to desmoglein (Dsg) 3 and develop mucosal blisters; while at the later stage of the disease (mucocutaneous PV), patients exhibit non-cross-reactive autoim...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 116(2005), 1 vom: 30. Juli, Seite 54-64
1. Verfasser: Salato, Valerie K (VerfasserIn)
Weitere Verfasser: Hacker-Foegen, Mary K, Lazarova, Zelmira, Fairley, Janet A, Lin, Mong-Shang
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Autoantibodies Cadherins DSG3 protein, human Desmoglein 3 Epitopes Peptide Fragments