Morphine modulates chemokine gene regulation in normal human astrocytes

Morphine modulates chemokine gene regulation in normal human astrocytes

Chemokines and their receptors have been implicated in the pathogenesis of neuroAIDS. Herein we describe the effects of morphine on the gene expression of beta chemokines and their receptors by primary normal human astrocytes (NHA). Our results show that NHA treated with morphine showed significant...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 115(2005), 3 vom: 31. Juni, Seite 323-32
1. Verfasser: Mahajan, Supriya D (VerfasserIn)
Weitere Verfasser: Schwartz, Stanley A, Aalinkeel, Ravikumar, Chawda, Ram P, Sykes, Donald E, Nair, Madhavan P N
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Chemokine CCL2 Chemokine CCL4 Cyclic AMP Response Element-Binding Protein Macrophage Inflammatory Proteins Receptors, Opioid, mu Naloxone mehr... 36B82AMQ7N Morphine 76I7G6D29C p38 Mitogen-Activated Protein Kinases EC 2.7.11.24