IL-17R activation of human airway smooth muscle cells induces CXCL-8 production via a transcriptional-dependent mechanism

IL-17R activation of human airway smooth muscle cells induces CXCL-8 production via a transcriptional-dependent mechanism

Airway neutrophilia has been recognized as a predominant feature of acute lung disorders. While it has been shown that IL-17 induces expression of the CXC chemokines in the airways leading to neutrophil recruitment, the IL-17R expression in human ASM cells and the molecular mechanism by which IL-17...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 115(2005), 3 vom: 31. Juni, Seite 268-76
1. Verfasser: Rahman, M S (VerfasserIn)
Weitere Verfasser: Yang, Jie, Shan, Lian Yu, Unruh, Helmut, Yang, Xi, Halayko, Andrew J, Gounni, Abdelilah Soussi
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't IL17RA protein, human Interleukin-17 Interleukin-8 RNA, Messenger Receptors, Interleukin Receptors, Interleukin-17