Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model

Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model

Tumor necrosis factor (TNF) antagonism with monoclonal antibodies is an effective therapy for severe Crohn's disease and rheumatoid arthritis. Recent studies have suggested that induction of apoptosis of inflammatory cells contributes to this therapeutic effect. We investigated whether inflixim...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 115(2005), 3 vom: 31. Juni, Seite 250-9
1. Verfasser: Shen, Chong (VerfasserIn)
Weitere Verfasser: Maerten, Philippe, Geboes, Karel, Van Assche, Gert, Rutgeerts, Paul, Ceuppens, Jan L
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal Immunoglobulin G Receptors, IgG Receptors, Tumor Necrosis Factor Infliximab B72HH48FLU Etanercept OP401G7OJC