Rapid emergence of escape mutants following infection with murine cytomegalovirus in immunodeficient mice

Rapid emergence of escape mutants following infection with murine cytomegalovirus in immunodeficient mice

Natural killer (NK) cells play a crucial role in the initial host defense against pathogens such as murine cytomegalovirus (MCMV). They respond rapidly and effectively control pathogen replication while the adaptive immune system is being activated. However, in the absence of an adaptive immune syst...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 115(2005), 1 vom: 01. Apr., Seite 61-9
1. Verfasser: French, Anthony R (VerfasserIn)
Weitere Verfasser: Pingel, Jeanette T, Kim, Sungjin, Yang, Liping, Yokoyama, Wayne M
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Antigens, Ly DNA, Viral Lectins, C-Type Receptors, NK Cell Lectin-Like