In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation

In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation

Regulatory T cells (Tregs) have been shown to be critical in the balance between autoimmunity and tolerance and have been implicated in several human autoimmune diseases. However, the small number of Tregs in peripheral blood limits their therapeutic potential. Therefore, we developed a protocol tha...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 115(2005), 1 vom: 01. Apr., Seite 3-9
1. Verfasser: Earle, K E (VerfasserIn)
Weitere Verfasser: Tang, Q, Zhou, X, Liu, W, Zhu, S, Bonyhadi, M L, Bluestone, J A
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. CCR6 protein, human FOXP1 protein, human Forkhead Transcription Factors HLA-DR Antigens Interleukin-2 Receptors, CCR6 mehr... Receptors, Chemokine Receptors, Interleukin-2 Repressor Proteins L-Selectin 126880-86-2