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NLM154863343 |
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DE-627 |
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231223s2005 xx ||||| 00| ||chi c |
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|a pubmed25n0516.xml
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|a (DE-627)NLM154863343
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|a (NLM)15836830
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Hu, Zhen-jie
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Effects of continuous veno-venous hemofiltration on the hemodynamics of sheep with endotoxic shock
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| 264 |
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|c 2005
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 15.12.2009
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|a Date Revised 19.04.2005
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE: To study the influence of continuous veno-venous hemofiltration (CVVH) on the hemodynamics and the prognosis of sheep with endotoxic shock
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|a METHODS: Endotoxic shock was induced by intravenous infusion of lipopolysaccharide, L-2880, to sheep, and the animals were randomly divided to control group (NHF, endotoxin only) or treatment group (HF, endotoxin+CVVH). In the latter groups a zero-balanced CVVH was instituted with an ultrafiltration rate of 40 ml x kg(-1) x h(-1) and a blood flow rate of 80 ml/min. The hemodynamic parameters were monitored
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|a RESULTS: After the administration of endotoxin, the mean arterial pressure (MAP) was decreased significantly, while mean pulmonary artery pressure (MPAP) and cardiac index (CI) increased significantly in both groups (P<0.05 or P<0.01). With CVVH, MAP and stroke volume (SV) were increased significantly, and were significantly higher than that of NHF group (P<0.05 or P<0.01). CI declined progressively in NHF group and significantly lower than that of HF group, in which there was no significant change(P<0.05). No significant difference in MPAP was found between two groups (P>0.05). Moreover, plasma lactate levels were lower in NHF group than in HF group (P<0.05). After 5 hours, the sheep in HF group all survived, and 2 sheep of NHF group died
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|a CONCLUSION: Intravenous infusion of endotoxin could produce endotoxic shock in sheep. CVVH was shown to have a beneficial effect on the hemodynamics, and it gave a better prognosis in endotoxic, indicating that it might be important method to treat endotoxic shock
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|a English Abstract
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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| 650 |
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|a Endotoxins
|2 NLM
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| 700 |
1 |
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|a Liu, Li-xia
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sun, Li-xiao
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Yong
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 17(2005), 4 vom: 18. Apr., Seite 234-7
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
1 |
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|g volume:17
|g year:2005
|g number:4
|g day:18
|g month:04
|g pages:234-7
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|d 17
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|h 234-7
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