NEMO Delta 4-10 deletion of NEMO gene in Chinese incontinentia pigmenti cases

NEMO Delta 4-10 deletion of NEMO gene in Chinese incontinentia pigmenti cases

OBJECTIVE: Incontinentia pigmenti (IP) is a rare X-linked dominant disorder that affects ectodermal tissues. In IP, mutations in NEMO lead to the complete loss of NF-kB activation creating a susceptibility to cellular apoptosis in response to TNF-alpha. Recently, a second nonfunctional copy of the g...

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Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 43(2005), 2 vom: 18. Feb., Seite 89-92
1. Verfasser: Li, Li (VerfasserIn)
Weitere Verfasser: Song, Guo-wei, DU, Jun-bao, Liu, Ji-rong, Xu, Fang-sheng, Liu, Xiao-yan, Zhang, Ting
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't IKBKG protein, human I-kappa B Kinase EC 2.7.11.10