Degradation and metabolite production of tylosin in anaerobic and aerobic swine-manure lagoons

Watershed contamination from antibiotics is becoming a critical issue because of increased numbers of confined animal-feeding operations and the use of antibiotics in animal production. To understand the fate of tylosin in manure before it is land-applied, degradation in manure lagoon slurries at 22...

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Veröffentlicht in:Water environment research : a research publication of the Water Environment Federation. - 1998. - 77(2005), 1 vom: 26. Jan., Seite 49-56
1. Verfasser: Kolz, A C (VerfasserIn)
Weitere Verfasser: Moorman, T B, Ong, S K, Scoggin, K D, Douglass, E A
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Water environment research : a research publication of the Water Environment Federation
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Anti-Bacterial Agents Manure Water Pollutants, Chemical Tylosin YEF4JXN031
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245 1 0 |a Degradation and metabolite production of tylosin in anaerobic and aerobic swine-manure lagoons 
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520 |a Watershed contamination from antibiotics is becoming a critical issue because of increased numbers of confined animal-feeding operations and the use of antibiotics in animal production. To understand the fate of tylosin in manure before it is land-applied, degradation in manure lagoon slurries at 22 degrees C was studied. Tylosin disappearance followed a biphasic pattern, where rapid initial loss was followed by a slow removal phase. The 90% disappearance times for tylosin, relomycin (tylosin D), and desmycosin (tylosin B) in anaerobically incubated slurries were 30 to 130 hours. Aerating the slurries reduced the 90% disappearance times to between 12 and 26 hours. Biodegradation and abiotic degradation occur, but strong sorption to slurry solids was probably the primary mechanism of tylosin disappearance. Dihydrodesmycosin and an unknown degradate with molecular mass of m/z 934.5 were detected. Residual tylosin remained in slurry after eight months of incubation, indicating that degradation in lagoons is incomplete and that residues will enter agricultural fields 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Anti-Bacterial Agents  |2 NLM 
650 7 |a Manure  |2 NLM 
650 7 |a Water Pollutants, Chemical  |2 NLM 
650 7 |a Tylosin  |2 NLM 
650 7 |a YEF4JXN031  |2 NLM 
700 1 |a Moorman, T B  |e verfasserin  |4 aut 
700 1 |a Ong, S K  |e verfasserin  |4 aut 
700 1 |a Scoggin, K D  |e verfasserin  |4 aut 
700 1 |a Douglass, E A  |e verfasserin  |4 aut 
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