Direct conjugation of semiconductor nanoparticles with proteins

Nanocrystalline CdS particles directly conjugated with bovine serum albumin (BSA) protein were prepared by applying the supercritical fluid processing technique, rapid expansion of a supercritical solution into a liquid solvent. The direct conjugation takes advantage of the unique features of the pr...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 21(2005), 5 vom: 01. März, Seite 2008-11
1. Verfasser: Meziani, Mohammed J (VerfasserIn)
Weitere Verfasser: Pathak, Pankaj, Harruff, Barbara A, Hurezeanu, Razvan, Sun, Ya-Ping
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Cadmium Compounds Sulfides cadmium sulfide 057EZR4Z7Q Serum Albumin, Bovine 27432CM55Q
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520 |a Nanocrystalline CdS particles directly conjugated with bovine serum albumin (BSA) protein were prepared by applying the supercritical fluid processing technique, rapid expansion of a supercritical solution into a liquid solvent. The direct conjugation takes advantage of the unique features of the process for nanoparticle formation. The BSA-conjugated CdS nanoparticles in stable aqueous suspension or in the solid state were characterized by using microscopy, X-ray diffraction, and optical spectroscopy methods. The results show that well-dispersed CdS nanoparticles are coated with BSA in a core-shell-like arrangement and that the protein species associated with the nanoparticles remain functional according to the modified Lowry assay. These BSA-conjugated CdS nanoparticles are also strongly luminescent, with the luminescence spectrum contributed to primarily by the exciton emission 
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650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
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700 1 |a Pathak, Pankaj  |e verfasserin  |4 aut 
700 1 |a Harruff, Barbara A  |e verfasserin  |4 aut 
700 1 |a Hurezeanu, Razvan  |e verfasserin  |4 aut 
700 1 |a Sun, Ya-Ping  |e verfasserin  |4 aut 
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