Surface complexation of DNA with insoluble monolayers. Influence of divalent counterions

DNA interacts with insoluble monolayers made of cationic amphiphiles as well as with monolayers of zwitterionic lipids in the presence of divalent ions. Binding to dioctadecyldimethylammonium bromide (DODAB) or distearoyl-sn-glycero-3-phosphocholine (DSPC) monolayers in the presence of calcium is ac...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 21(2005), 5 vom: 01. März, Seite 1900-7
1. Verfasser: McLoughlin, D (VerfasserIn)
Weitere Verfasser: Dias, R, Lindman, B, Cardenas, M, Nylander, T, Dawson, K, Miguel, M, Langevin, D
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Cations, Divalent Quaternary Ammonium Compounds dimethyldioctadecylammonium 251IW5I21C DNA 9007-49-2 calf thymus DNA 91080-16-9
LEADER 01000naa a22002652 4500
001 NLM153796863
003 DE-627
005 20231223064728.0
007 tu
008 231223s2005 xx ||||| 00| ||eng c
028 5 2 |a pubmed24n0513.xml 
035 |a (DE-627)NLM153796863 
035 |a (NLM)15723487 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a McLoughlin, D  |e verfasserin  |4 aut 
245 1 0 |a Surface complexation of DNA with insoluble monolayers. Influence of divalent counterions 
264 1 |c 2005 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 13.06.2006 
500 |a Date Revised 15.11.2012 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a DNA interacts with insoluble monolayers made of cationic amphiphiles as well as with monolayers of zwitterionic lipids in the presence of divalent ions. Binding to dioctadecyldimethylammonium bromide (DODAB) or distearoyl-sn-glycero-3-phosphocholine (DSPC) monolayers in the presence of calcium is accompanied by monolayer expansion. For the positively charged DODAB monolayer, this causes a decrease of surface potential, while an increase is observed for the DSPC monolayers. Binding to dipalmitoyl-sn-glycero-3-phosphocholine preserves most of the liquid expanded-liquid condensed coexistence region. The liquid condensed domains adopt an elongated morphology in the presence of DNA, especially in the presence of calcium. The interaction of DNA with phospholipid monolayers is ion specific: the presence of calcium leads to a stronger interaction than magnesium and barium. These results were confirmed by bulk complexation studies 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Cations, Divalent  |2 NLM 
650 7 |a Quaternary Ammonium Compounds  |2 NLM 
650 7 |a dimethyldioctadecylammonium  |2 NLM 
650 7 |a 251IW5I21C  |2 NLM 
650 7 |a DNA  |2 NLM 
650 7 |a 9007-49-2  |2 NLM 
650 7 |a calf thymus DNA  |2 NLM 
650 7 |a 91080-16-9  |2 NLM 
700 1 |a Dias, R  |e verfasserin  |4 aut 
700 1 |a Lindman, B  |e verfasserin  |4 aut 
700 1 |a Cardenas, M  |e verfasserin  |4 aut 
700 1 |a Nylander, T  |e verfasserin  |4 aut 
700 1 |a Dawson, K  |e verfasserin  |4 aut 
700 1 |a Miguel, M  |e verfasserin  |4 aut 
700 1 |a Langevin, D  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 21(2005), 5 vom: 01. März, Seite 1900-7  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:21  |g year:2005  |g number:5  |g day:01  |g month:03  |g pages:1900-7 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 21  |j 2005  |e 5  |b 01  |c 03  |h 1900-7