Functionally divergent T lymphocyte responses induced by modification of a self-peptide from a tumor-associated antigen

Functionally divergent T lymphocyte responses induced by modification of a self-peptide from a tumor-associated antigen

The N- and C-terminal flanking domains of the invariant chain peptide, CLIP, have remarkable immunological properties. Addition of these flanking domains to a foreign peptide antigen increases its immunologic potency. The present studies evaluated whether altering a peptide ligand from the tumor-ass...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 114(2005), 3 vom: 25. März, Seite 307-19
1. Verfasser: Hess, Allan D (VerfasserIn)
Weitere Verfasser: Thoburn, Christopher J, Miura, Yuji, Bright, Emilie C
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, U.S. Gov't, P.H.S. Antigens, Differentiation, B-Lymphocyte Antigens, Neoplasm Cancer Vaccines Cytokines Histocompatibility Antigens Class II Peptide Fragments invariant chain Receptor, ErbB-2 EC 2.7.10.1