Preservation and redirection of HPV16E7-specific T cell receptors for immunotherapy of cervical cancer

Human papilloma virus (HPV) type 16 infections of the genital tract are associated with the development of cervical cancer (CxCa) in women. HPV16-derived oncoproteins E6 and E7 are expressed constitutively in these lesions and might therefore be attractive candidates for T-cell-mediated adoptive imm...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 114(2005), 2 vom: 10. Feb., Seite 119-29
1. Verfasser: Scholten, Kirsten B J (VerfasserIn)
Weitere Verfasser: Schreurs, Marco W J, Ruizendaal, Janneke J, Kueter, Esther W M, Kramer, Duco, Veenbergen, Sharon, Meijer, Chris J L M, Hooijberg, Erik
Format: Aufsatz
Sprache:English
Veröffentlicht: 2005
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Oncogene Proteins, Viral Papillomavirus E7 Proteins RNA, Viral Receptors, Antigen, T-Cell oncogene protein E7, Human papillomavirus type 16