Mixed Ehrlichia canis, Hepatozoon canis, and presumptive Anaplasma phagocytophilum infection in a dog

A 5-month-old, female, mongrel dog was admitted to the Clinic of Companion Animal Medicine, Aristotle University of Thessaloniki, Greece, with depression, anorexia, fever, peripheral lymphadenopathy, splenomegaly, oculonasal discharge, nonregenerative anemia, and mild thrombocytopenia. Cytology of G...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 33(2004), 4 vom: 26., Seite 249-51
1. Verfasser: Mylonakis, Mathio E (VerfasserIn)
Weitere Verfasser: Koutinas, Alex F, Baneth, Gad, Polizopoulou, Zoe, Fytianou, Anna
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Case Reports Journal Article
LEADER 01000caa a22002652 4500
001 NLM152371001
003 DE-627
005 20250206013652.0
007 tu
008 231223s2004 xx ||||| 00| ||eng c
028 5 2 |a pubmed25n0508.xml 
035 |a (DE-627)NLM152371001 
035 |a (NLM)15570564 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Mylonakis, Mathio E  |e verfasserin  |4 aut 
245 1 0 |a Mixed Ehrlichia canis, Hepatozoon canis, and presumptive Anaplasma phagocytophilum infection in a dog 
264 1 |c 2004 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 17.02.2005 
500 |a Date Revised 09.11.2019 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a A 5-month-old, female, mongrel dog was admitted to the Clinic of Companion Animal Medicine, Aristotle University of Thessaloniki, Greece, with depression, anorexia, fever, peripheral lymphadenopathy, splenomegaly, oculonasal discharge, nonregenerative anemia, and mild thrombocytopenia. Cytology of Giemsa-stained buffy coat, bone marrow, and lymph node aspiration smears revealed numerous morulae in mononuclear leukocytes and in neutrophils, and Hepatozoon canis gamonts in neutrophils. The dog was seropositive to Ehrlichia canis (immunofluorescence assay [IFA]) and Hepatozoon canis (ELISA) but not to Anaplasma phagocytophilum (IFA). A nested polymerase chain reaction performed on bone marrow aspirates was positive for E canis. This method was not applied for the detection of A phagocytophilum. Treatment with doxycycline and imidocarb dipropionate resulted in both clinical and parasitologic cure. This is the first reported case of a mixed infection with E canis, H canis, and presumptive A phagocytophilum. The findings emphasize the value of cytology in offering a quick and inexpensive diagnosis in mixed tick-borne infections of dogs 
650 4 |a Case Reports 
650 4 |a Journal Article 
700 1 |a Koutinas, Alex F  |e verfasserin  |4 aut 
700 1 |a Baneth, Gad  |e verfasserin  |4 aut 
700 1 |a Polizopoulou, Zoe  |e verfasserin  |4 aut 
700 1 |a Fytianou, Anna  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Veterinary clinical pathology  |d 1975  |g 33(2004), 4 vom: 26., Seite 249-51  |w (DE-627)NLM098159984  |x 0275-6382  |7 nnns 
773 1 8 |g volume:33  |g year:2004  |g number:4  |g day:26  |g pages:249-51 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 33  |j 2004  |e 4  |b 26  |h 249-51