Toxic effect of pharmaceuticals on methanogenesis

Pharmaceuticals present in sewage may inhibit the biological processes in a sewage treatment plant. In this work, the toxic-effect of six pharmaceuticals (carbamazepine, sulfamethoxazole, propranolol hydrochloride, diclofenac sodium, ofloxacin and clofibric acid) on the anaerobic digestion process i...

Description complète

Détails bibliographiques
Publié dans:Water science and technology : a journal of the International Association on Water Pollution Research. - 1986. - 50(2004), 5 vom: 15., Seite 335-40
Auteur principal: Fountoulakis, M (Auteur)
Autres auteurs: Drillia, P, Stamatelatou, K, Lyberatos, G
Format: Article
Langue:English
Publié: 2004
Accès à la collection:Water science and technology : a journal of the International Association on Water Pollution Research
Sujets:Journal Article Research Support, Non-U.S. Gov't Pharmaceutical Preparations Sewage Diclofenac 144O8QL0L1 Carbamazepine 33CM23913M Clofibric Acid 53PF01Q249 plus... Propranolol 9Y8NXQ24VQ Ofloxacin A4P49JAZ9H Sulfamethoxazole JE42381TNV Methane OP0UW79H66
Description
Résumé:Pharmaceuticals present in sewage may inhibit the biological processes in a sewage treatment plant. In this work, the toxic-effect of six pharmaceuticals (carbamazepine, sulfamethoxazole, propranolol hydrochloride, diclofenac sodium, ofloxacin and clofibric acid) on the anaerobic digestion process is assessed. Acetoclastic methanogenes are the most sensitive group of microorganisms participating in the anaerobic digestion process. Appropriate toxicity tests for these microorganisms were then based on assessing the impact of pharmaceuticals on the specific methanogenic activity (SMA) of the anaerobic biomass. The toxicity was expressed by the IC80 and IC50 values, i.e. the concentration at which bioactivity was 80% and 50% of the control, respectively. Results showed that the pharmaceuticals tested caused a mild inhibition to the methanogenes in most cases, related directly to the tendency of the compounds to adsorb on the anaerobic biomass
Description:Date Completed 31.01.2005
Date Revised 21.11.2013
published: Print
Citation Status MEDLINE
ISSN:0273-1223