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01000caa a22002652 4500 |
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NLM151479011 |
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DE-627 |
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20231227123435.0 |
| 007 |
tu |
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231223s2004 xx ||||| 00| ||eng c |
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|a pubmed24n1221.xml
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|a (DE-627)NLM151479011
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| 035 |
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|a (NLM)15475374
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Chen, Shaorong
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Bcl-2 family members localize to tobacco chloroplasts and inhibit programmed cell death induced by chloroplast-targeted herbicides
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| 264 |
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|c 2004
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 03.02.2005
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|a Date Revised 13.12.2023
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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| 520 |
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|a In mammalian cells, apoptosis is often mediated via organelles. While apoptotic-like cell death occurs in plants, the mechanistic details are unresolved. Transgenic tobacco plants have been generated that harbour selected animal anti-apoptotic genes. Subcellular fractionation followed by western blot analysis indicated that chloroplasts serve as a location for these animal anti-apoptotic proteins in addition to the established mitochondrial location. To explore the functional significance of this observation, tobacco plants were treated with three chloroplast-directed herbicides. Wild-type plants died and exhibited features associated with apoptosis. Transgenic plants survived and did not show any apoptotic-like characteristics. Moreover, the herbicide-induced apoptotic-like cell death was light requiring. It was concluded that chloroplasts may be involved in mediating certain types of plant programmed cell death
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| 650 |
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|a Journal Article
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| 650 |
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4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
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| 650 |
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7 |
|a Apoptosis Regulatory Proteins
|2 NLM
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| 650 |
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7 |
|a BCL2L1 protein, human
|2 NLM
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| 650 |
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7 |
|a Caenorhabditis elegans Proteins
|2 NLM
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| 650 |
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7 |
|a Ced-9 protein, C elegans
|2 NLM
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| 650 |
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7 |
|a Herbicides
|2 NLM
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| 650 |
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7 |
|a Proto-Oncogene Proteins
|2 NLM
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| 650 |
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7 |
|a Proto-Oncogene Proteins c-bcl-2
|2 NLM
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| 650 |
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7 |
|a bcl-X Protein
|2 NLM
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| 700 |
1 |
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|a Dickman, Martin B
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 55(2004), 408 vom: 27. Dez., Seite 2617-23
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnns
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| 773 |
1 |
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|g volume:55
|g year:2004
|g number:408
|g day:27
|g month:12
|g pages:2617-23
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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|a GBV_NLM
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| 912 |
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|a GBV_ILN_350
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| 951 |
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|a AR
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| 952 |
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|d 55
|j 2004
|e 408
|b 27
|c 12
|h 2617-23
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