Human multiple myeloma cells express peroxisome proliferator-activated receptor gamma and undergo apoptosis upon exposure to PPARgamma ligands

Multiple myeloma is essentially an incurable malignancy and it is therefore of great interest to develop new therapeutic approaches. We previously reported that human B cell-lymphomas express the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARgamma) and are killed by PPARgamm...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 113(2004), 2 vom: 29. Nov., Seite 203-13
Auteur principal: Ray, Denise M (Auteur)
Autres auteurs: Bernstein, Steven H, Phipps, Richard P
Format: Article
Langue:English
Publié: 2004
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. 15-deoxy-delta(12,14)-prostaglandin J2 Immunologic Factors Interleukin-6 Ligands PPAR gamma RNA, Messenger plus... Thiazolidinediones Tretinoin 5688UTC01R Caspases EC 3.4.22.- Prostaglandin D2 RXY07S6CZ2 ciglitazone U8QXS1WU8G