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231223s2004 xx ||||| 00| ||eng c |
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|a pubmed25n0504.xml
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|a (DE-627)NLM15125060X
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|a (NLM)15451469
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Chierakul, Wirongrong
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Differential expression of interferon-gamma and interferon-gamma-inducing cytokines in Thai patients with scrub typhus or leptospirosis
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| 264 |
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|c 2004
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 19.11.2004
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|a Date Revised 21.11.2008
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|a published: Print
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|a Citation Status MEDLINE
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|a Interferon (IFN)-gamma plays an important role in the induction of a type 1 immune response against intracellular pathogens. We compared the plasma levels of IFN-gamma and IFN-gamma-inducing cytokines in adult Thai patients with scrub typhus, caused by the obligate intracellular bacterium Orientia tsutsugamushi, and leptospirosis, caused by extracellular Leptospira interrogans. IFN-gamma, interleukin (IL)-18, and IL-15 levels were elevated only in patients with scrub typhus, whereas IL-12p40 and tumor necrosis factor-alpha concentrations were elevated in both patient groups, although more so in scrub typhus. These data suggest a role for a cell-mediated immune response in host defense against O. tsutsugamushi
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| 650 |
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|a Comparative Study
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| 650 |
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|a Journal Article
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| 650 |
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|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Interleukin-15
|2 NLM
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| 650 |
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7 |
|a Interleukin-18
|2 NLM
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| 650 |
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7 |
|a Tumor Necrosis Factor-alpha
|2 NLM
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| 650 |
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7 |
|a Interferon-gamma
|2 NLM
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| 650 |
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7 |
|a 82115-62-6
|2 NLM
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| 700 |
1 |
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|a de Fost, Maaike
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Suputtamongkol, Yupin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Limpaiboon, Roongreung
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Dondorp, Arjen
|e verfasserin
|4 aut
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| 700 |
1 |
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|a White, Nicholas J
|e verfasserin
|4 aut
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| 700 |
1 |
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|a van der Poll, Tom
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 113(2004), 2 vom: 29. Nov., Seite 140-4
|w (DE-627)NLM098196855
|x 1521-6616
|7 nnns
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| 773 |
1 |
8 |
|g volume:113
|g year:2004
|g number:2
|g day:29
|g month:11
|g pages:140-4
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|a AR
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| 952 |
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|d 113
|j 2004
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|c 11
|h 140-4
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