3-d reconstruction of 2-D crystals in real space

A new algorithm for three-dimensional reconstruction of two-dimensional crystals from projections is presented, and its applicability to biological macromolecules imaged using transmission electron microscopy (TEM) is investigated. Its main departures from the traditional approach is that it works i...

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Veröffentlicht in:IEEE transactions on image processing : a publication of the IEEE Signal Processing Society. - 1997. - 13(2004), 4 vom: 10. Apr., Seite 549-61
1. Verfasser: Marabini, Roberto (VerfasserIn)
Weitere Verfasser: Sorzano, Carlos O S, Matej, Samuel, Fernández, José J, Carazo, José M, Herman, Gabor T
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
Schlagworte:Comparative Study Evaluation Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Validation Study Capsid Proteins Macromolecular Substances
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100 1 |a Marabini, Roberto  |e verfasserin  |4 aut 
245 1 0 |a 3-d reconstruction of 2-D crystals in real space 
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500 |a ErratumIn: IEEE Trans Image Process. 2004 Aug;13(8):1157 
500 |a Citation Status MEDLINE 
520 |a A new algorithm for three-dimensional reconstruction of two-dimensional crystals from projections is presented, and its applicability to biological macromolecules imaged using transmission electron microscopy (TEM) is investigated. Its main departures from the traditional approach is that it works in real space, rather than in Fourier space, and it is iterative. This has the advantage of making it convenient to introduce additional constraints (such as the support of the function to be reconstructed, which may be known from alternative measurements) and has the potential of more accurately modeling the TEM image formation process. Phantom experiments indicate the superiority of the new approach even without the introduction of constraints in addition to the projection data 
650 4 |a Comparative Study 
650 4 |a Evaluation Study 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, P.H.S. 
650 4 |a Validation Study 
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700 1 |a Sorzano, Carlos O S  |e verfasserin  |4 aut 
700 1 |a Matej, Samuel  |e verfasserin  |4 aut 
700 1 |a Fernández, José J  |e verfasserin  |4 aut 
700 1 |a Carazo, José M  |e verfasserin  |4 aut 
700 1 |a Herman, Gabor T  |e verfasserin  |4 aut 
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