Determination of Canine Factor VIII-related Antigen Using Commercial Antihuman F VIII Serum
Factor VIII-related antigen (F VIII:AGN) in 21 canine plasma samples was assayed by immunoelectrophoresis using a rabbit anticanine F VIII serum prepared from a canine F VIII concentrate and a commercial rabbit antihuman F VIII serum. A good correlation existed (r value 0.916) between the antigen le...
| Veröffentlicht in: | Veterinary clinical pathology. - 1975. - 9(1980), 1 vom: 20., Seite 31-5 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1980
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| Zugriff auf das übergeordnete Werk: | Veterinary clinical pathology |
| Schlagworte: | Journal Article |
| Zusammenfassung: | Factor VIII-related antigen (F VIII:AGN) in 21 canine plasma samples was assayed by immunoelectrophoresis using a rabbit anticanine F VIII serum prepared from a canine F VIII concentrate and a commercial rabbit antihuman F VIII serum. A good correlation existed (r value 0.916) between the antigen levels obtained using the two sera. In normal dogs the plasma F VIII:AGN level was 95 +/- 39% (Mean +/- SD) compared to 175 +/- 40% in dogs with severe hemophilia A and 17 +/- 15% in dogs with von Willebrand's disease. It was concluded that there was sufficient cross reactivity between canine F VIII and commercial rabbit antihuman F VIII serum to make the latter useful in the differential diagnosis of F VIII deficiencies in the dog |
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| Beschreibung: | Date Revised 20.11.2019 published: Print Citation Status PubMed-not-MEDLINE |
| ISSN: | 1939-165X |