Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease

Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease

4-1BB ligand (L) expressed on antigen presenting cells (APC) interacts with 4-1BB, expressed on activated T cells and this interaction costimulates T cells to secrete cytokines and to proliferate. We investigated whether 4-1BB/4-1BBL interactions might be involved in the pathogenesis of Crohn's...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 112(2004), 3 vom: 12. Sept., Seite 239-46
1. Verfasser: Maerten, Philippe (VerfasserIn)
Weitere Verfasser: Geboes, Karel, De Hertogh, Gert, Shen, Chong, Cadot, Pascal, Bullens, Dominique M A, Van Assche, Gert, Penninckx, Freddy, Rutgeerts, Paul, Ceuppens, Jan L
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't 4-1BB Ligand Antigens, CD RNA, Messenger Receptors, Nerve Growth Factor Receptors, Tumor Necrosis Factor TNFRSF9 protein, human TNFSF9 protein, human Tumor Necrosis Factor Receptor Superfamily, Member 9 mehr... Tumor Necrosis Factor-alpha Interferon-gamma 82115-62-6