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231223s2004 xx ||||| 00| ||eng c |
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|a DE-627
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|e rakwb
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|a eng
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1 |
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|a Garza, Juan Méndez
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Multicompartment films made of alternate polyelectrolyte multilayers of exponential and linear growth
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|c 2004
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 09.06.2006
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|a Date Revised 10.08.2004
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|a published: Print
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|a Citation Status PubMed-not-MEDLINE
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|a The layer by layer deposition process of polyelectrolytes is used to construct films equipped with several compartments containing "free polyelectrolytes". Each compartment corresponds to a stratum of an exponentially growing polyelectrolyte multilayer film, and two consecutive compartments are separated by a stratum composed of a linearly growing multilayer that acts as a barrier preventing polyelectrolyte diffusion from one compartment to another. We use hyaluronic acid/poly(L-lysine) as the system to build the compartments and the poly(styrene sulfonate)/poly(allylamine) system for the barrier. Using confocal microscopy, it is shown that poly(L-lysine) diffuses only within the compartment in which it was initially introduced during the film construction and is thus unable to cross the barriers. Using fluorescein isothiocyanate as a pH indicator, it is also shown that although poly(styrene sulfonate)/poly(allylamine) multilayers act as a barrier for polyelectrolytes, they do not prevent proton diffusion through the film. Such films open the route for multiple functionalization of biomaterial coatings
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|a Journal Article
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1 |
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|a Schaaf, Pierre
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Muller, Sylvaine
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ball, Vincent
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Stoltz, Jean-François
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Voegel, Jean-Claude
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lavalle, Philippe
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1991
|g 20(2004), 17 vom: 17. Aug., Seite 7298-302
|w (DE-627)NLM098181009
|x 0743-7463
|7 nnns
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| 773 |
1 |
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|g volume:20
|g year:2004
|g number:17
|g day:17
|g month:08
|g pages:7298-302
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