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01000caa a22002652 4500 |
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NLM149796315 |
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DE-627 |
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20250205180354.0 |
| 007 |
tu |
| 008 |
231223s2004 xx ||||| 00| ||chi c |
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2 |
|a pubmed25n0499.xml
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|a (DE-627)NLM149796315
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| 035 |
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|a (NLM)15298807
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Zhang, Jing-xia
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Level of tissue plasminogen activator protein in pulmonary artery in acute pulmonary thromboembolism in rabbit
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| 264 |
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1 |
|c 2004
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 08.09.2009
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| 500 |
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|a Date Revised 09.08.2004
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a OBJECTIVE: To study the changes in tissue plasminogen activator(t-PA) protein in pulmonary artery and its clinical significance after acute pulmonary thromboembolism (PTE)
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| 520 |
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|a METHODS: Thirty rabbits were randomly divided into four groups after replicating a model of acute PTE in rabbit by thrombi occlusion method. Specimens were obtained from both normal and morbid pulmonary artery 3, 8 and 24 hours after APE, and protein contents of t-PA were determined using immunohistochemical method
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| 520 |
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|a RESULTS: A few endothelial cells and smooth muscle cells of the normal pulmonary artery were positive for t-PA. After 3 hours of PTE, there was no significant changes in t-PA positive stain among embolismic, non-embolismic and normal pulmonary artery. After 8 and 24 hours of PTE, strong positive staining was found in the residual endothelial cells and a part of smooth muscle cells (all P<0.01)
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|a CONCLUSION: There is significantly strong positive staining for t-PA in the pulmonary artery wall after pulmonary embolism, implying that the local fibrinolysis activity was enhanced, and it might be helpful for lysis of the embolus
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| 650 |
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4 |
|a English Abstract
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| 650 |
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4 |
|a Journal Article
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| 650 |
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4 |
|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Tissue Plasminogen Activator
|2 NLM
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| 650 |
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7 |
|a EC 3.4.21.68
|2 NLM
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| 700 |
1 |
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|a Sun, Gen-yi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chen, Yong-li
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Pei-xian
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yuan, Zhi-ming
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhou, Yu-ling
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 16(2004), 8 vom: 06. Aug., Seite 481-3
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
1 |
8 |
|g volume:16
|g year:2004
|g number:8
|g day:06
|g month:08
|g pages:481-3
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| 912 |
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|a GBV_USEFLAG_A
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| 912 |
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|a SYSFLAG_A
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| 912 |
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|a GBV_NLM
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| 912 |
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|a GBV_ILN_350
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| 951 |
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|a AR
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| 952 |
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|d 16
|j 2004
|e 8
|b 06
|c 08
|h 481-3
|