Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells

Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells

Signals transmitted by binding of Fas ligand (FasL) to the Fas receptor (CD95/Apo-1) have pleiotropic effects on cellular function that present opportunities for therapeutic applications. For example, depending on the circumstances, overexpression of FasL can enhance, prevent, or reverse growth of s...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 112(2004), 1 vom: 16. Juli, Seite 54-65
1. Verfasser: Modiano, Jaime F (VerfasserIn)
Weitere Verfasser: Sun, Juan, Lang, Julie, Vacano, Guido, Patterson, David, Chan, Daniel, Franzusoff, Alex, Gianani, Roberto, Meech, Sandra J, Duke, Richard, Bellgrau, Donald
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Fas Ligand Protein Fasl protein, mouse Membrane Glycoproteins