Cytokines modulate cilomilast response in lung fibroblasts

Cytokines modulate cilomilast response in lung fibroblasts

Fibroblasts, as a major source of extracellular interstitial connective tissue matrix, play an important role in wound healing and the development of fibrosis. The phosphodiesterase (PDE) 4 inhibitor cilomilast inhibits fibroblast chemotaxis and fibroblast-mediated gel contraction. Using the Boyden...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 111(2004), 3 vom: 01. Juni, Seite 297-302
1. Verfasser: Kohyama, Tadashi (VerfasserIn)
Weitere Verfasser: Liu, Xiangde, Wen, Fu-Qiang, Kobayashi, Tetsu, Fang, Qiuhong, Abe, Shinji, Cieslinski, Lenora, Barnette, Mary S, Rennard, Stephen I
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Bronchodilator Agents Carboxylic Acids Cyclohexanecarboxylic Acids Cytokines Interleukin-1 Nitriles Recombinant Proteins mehr... Interleukin-4 207137-56-2 Cilomilast 8ATB1C1R6X Collagen 9007-34-5 Dinoprostone K7Q1JQR04M