T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis
Epitope spreading has been implicated in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and human multiple sclerosis (MS). T cell epitope spreading has been demonstrated in rodents for myelin basic protein (MBP) and proteolipid protein (PLP) determinants, but not for myelin olig...
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 111(2004), 1 vom: 01. Apr., Seite 53-60 |
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Weitere Verfasser: | , , , , , , |
Format: | Aufsatz |
Sprache: | English |
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2004
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Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Epitopes, T-Lymphocyte HLA-DR4 Antigen MOG peptide 97-108 MOG protein, human Mog protein, mouse Myelin Proteins Myelin-Associated Glycoprotein mehr... |