T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis

T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis

Epitope spreading has been implicated in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) and human multiple sclerosis (MS). T cell epitope spreading has been demonstrated in rodents for myelin basic protein (MBP) and proteolipid protein (PLP) determinants, but not for myelin olig...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 111(2004), 1 vom: 01. Apr., Seite 53-60
1. Verfasser: Klehmet, Juliane (VerfasserIn)
Weitere Verfasser: Shive, Carey, Guardia-Wolff, Rocio, Petersen, Ines, Spack, Edward G, Boehm, Bernhard O, Weissert, Robert, Forsthuber, Thomas G
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Epitopes, T-Lymphocyte HLA-DR4 Antigen MOG peptide 97-108 MOG protein, human Mog protein, mouse Myelin Proteins Myelin-Associated Glycoprotein mehr... Myelin-Oligodendrocyte Glycoprotein Peptide Fragments