MHC Class II tetramers and the pursuit of antigen-specific T cells : define, deviate, delete

Selective expansion and activation of a very small number of antigen-specific CD4(+) T cells is a remarkable and essential property of the adaptive immune response. Antigen-specific T cells were until recently identified only indirectly by functional assays, such as antigen-induced cytokine secretio...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 110(2004), 3 vom: 15. März, Seite 232-42
1. Verfasser: Mallone, Roberto (VerfasserIn)
Weitere Verfasser: Nepom, Gerald T
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, U.S. Gov't, P.H.S. Review Antigens Epitopes, T-Lymphocyte Histocompatibility Antigens Class II Receptors, Antigen, T-Cell