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231223s2004 xx ||||| 00| ||chi c |
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|a pubmed25n0490.xml
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|a (DE-627)NLM147107881
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|a (NLM)15009961
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a chi
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| 100 |
1 |
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|a Li, Jian-sheng
|e verfasserin
|4 aut
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|a Study on changes of neuron apoptosis after focal cerebral ischemia/reperfusion in the aged rats
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|c 2004
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 07.10.2004
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|a Date Revised 15.11.2006
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE: To study ultrastructured change and neuron apoptosis after focal cerebral ischemia/reperfusion (I/R) in the aged rats
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|a METHODS: The aged SD rats (20-21 months) and the young (4-5 months) were subjected to 3 hours of middle cerebral artery occulsion with the intraluminal filament technique, followed by reperfusion for 3 hours, 6 hours, 12 hours, 24 hours, 72 hours. The ultrastructure of brain, infarct zone and neuron apoptosis were observed
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|a RESULTS: The cerebral infarct zone increased in the aged rats with ischemia for 3 hours and I/R for 12 hours compared with those in the young. The brain injury was obviously deteriorated with I/R time longer, which was serious in the aged than that in the young. The neuron apoptosis increase with I/R time longer, and showed earlier and lasted longer in the aged
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|a CONCLUSION: The cerebral injury is serious and neuron apoptosis increase shows early and lasts longer
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|a English Abstract
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|a Journal Article
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| 650 |
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|a Research Support, Non-U.S. Gov't
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| 700 |
1 |
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|a Ren, Xiao-qiao
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Ke
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Zheng-guo
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kong, Ling-fei
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 16(2004), 3 vom: 01. März, Seite 151-4
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
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| 773 |
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|g volume:16
|g year:2004
|g number:3
|g day:01
|g month:03
|g pages:151-4
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|a AR
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|d 16
|j 2004
|e 3
|b 01
|c 03
|h 151-4
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