Utilizing Fcepsilon-Bak chimeric protein for studying IgE-FcepsilonRI interactions

We previously constructed a pro-apoptotic Fcepsilon-Bak chimeric protein, targeted against cells expressing the IgE high affinity receptor (FcepsilonRI). We demonstrated that the chimeric protein is internalized by target mast cells and kills them. These results, which constitute a promising basis f...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 110(2004), 1 vom: 01. Jan., Seite 89-99
Auteur principal: Belostotsky, Ruth (Auteur)
Autres auteurs: Lorberboum-Galski, Haya
Format: Article
Langue:English
Publié: 2004
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article BAK1 protein, human Bak1 protein, mouse Membrane Proteins Receptors, IgE Recombinant Fusion Proteins bcl-2 Homologous Antagonist-Killer Protein Immunoglobulin E 37341-29-0