Abnormal development of thymic dendritic and epithelial cells in human X-linked severe combined immunodeficiency

Abnormal development of thymic dendritic and epithelial cells in human X-linked severe combined immunodeficiency

The X-linked form of severe combined immunodeficiency (X-SCID) is caused by mutations in the common cytokine receptor gamma chain and results in lack of T and NK cells and defective B cells. Without immune reconstitution, X-SCID patients typically die from infection during infancy. This report descr...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 110(2004), 1 vom: 01. Jan., Seite 63-70
1. Verfasser: Hale, Laura P (VerfasserIn)
Weitere Verfasser: Buckley, Rebecca H, Puck, Jennifer M, Patel, Dhavalkumar D
Format: Aufsatz
Sprache:English
Veröffentlicht: 2004
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.