|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM144687186 |
| 003 |
DE-627 |
| 005 |
20250205072146.0 |
| 007 |
tu |
| 008 |
231223s2004 xx ||||| 00| ||chi c |
| 028 |
5 |
2 |
|a pubmed25n0482.xml
|
| 035 |
|
|
|a (DE-627)NLM144687186
|
| 035 |
|
|
|a (NLM)14764225
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a chi
|
| 100 |
1 |
|
|a Li, Tan-Shi
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Study on apoptosis of lung tissue cells in patients with severe brain injury complicated with aspiration-induced lung injury
|
| 264 |
|
1 |
|c 2004
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
|
| 338 |
|
|
|a Band
|b nc
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 29.07.2004
|
| 500 |
|
|
|a Date Revised 08.12.2020
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a OBJECTIVE: To investigate the role of apoptosis of pulmonary cells in aspiration induced lung injury in patients with severe brain injury with or without aspiration-induced lung injury
|
| 520 |
|
|
|a METHODS: The Glasgow scale (GCS) of 11 dead patients with severe closed brain injury was 3-8. There 11 cases were divided into aspiration-induced lung injury (AILI) and non-aspiration-induced lung injury (NAILI) groups. The plasma levels of tumor necrosis factor-alpha (TNF-alpha) and interleukin-8 (IL-8) were measured, and the ratio of apoptosis in lung tissue cells was also determined
|
| 520 |
|
|
|a RESULTS: The plasma levels of TNF-alpha and IL-8 in NAILI and AILI groups were (2.17+/-0.41)nug/L vs. (3.14+/-0.28)nug/L and (0.42+/-0.05)nug/L vs. (0.91+/-0.08) nug/L (P<0.05) respectively. Lung tissue cell apoptosis ratio was significantly higher in AILI group than NAILI group (P<0.01)
|
| 520 |
|
|
|a CONCLUSION: TNF-alpha and IL-8 may induce apoptosis in lung tissues through different signaling pathway. During the early phase of aspiration-induced lung injury complicating severe closed brain injury, apoptosis in cells of lung tissue may play a role in the pathogenes
|
| 650 |
|
4 |
|a Comparative Study
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
7 |
|a Interleukin-8
|2 NLM
|
| 650 |
|
7 |
|a Tumor Necrosis Factor-alpha
|2 NLM
|
| 700 |
1 |
|
|a Yin, Di-Cheng
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wu, Xu-Hui
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Song, Yang-Li
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Yin, Ming
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Shen, Hong
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a He, Quan-Ying
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
|d 1998
|g 16(2004), 2 vom: 06. Feb., Seite 97-9
|w (DE-627)NLM098227793
|x 1003-0603
|7 nnns
|
| 773 |
1 |
8 |
|g volume:16
|g year:2004
|g number:2
|g day:06
|g month:02
|g pages:97-9
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 16
|j 2004
|e 2
|b 06
|c 02
|h 97-9
|