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|a pubmed25n0482.xml
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|a (DE-627)NLM144522179
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|a (NLM)14746684
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a chi
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| 100 |
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|a Chen, Yu-zhi
|e verfasserin
|4 aut
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|a Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children
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|c 2003
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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|a Date Completed 20.05.2004
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|a Date Revised 07.06.2016
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|a published: Print
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|a Citation Status MEDLINE
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|a OBJECTIVE This study aimed to determine the relationship between individual allergens with current wheezing and bronchial hyperresponsiveness (BHR) in schoolchildren from three chinese cities: Beijing, Guangzhou and Hong Kong. METHODS Community-based random samples of 10-yr-old schoolchildren from the 3 cities were recruited for study using the International Study of Asthma and Allergies in Childhood (ISAAC) Phase II protocol. The subjects were studied by parental questionnaires (n = 10,902), skin-prick tests (n = 3478), and methacholine challenge tests (n = 608). RESULTS The highest prevalence rates of wheezing in the past 12 months (Beijing, 3.8%; Guangzhou, 3.4%; Hong Kong, 5.8%) and atopy (Beijing, 23.9%; Guangzhou, 30.8%; Hong Kong, 41.2%, defined as having <or= 1 positive skin-prick tests,) were seen in schoolchildren from Hong Kong. The highest prevalence rates of BHR (Beijing, 33.2%; Guangzhou, 45.8%; Hong Kong, 30.7%) were seen in schoolchildren from Guangzhou. Multivariate-logistic regression analyses revealed that sensitization to Dermatophagoides pteronyssinus [odds ratio ((OR)) = 4.48; 95% confidence interval ((CI)); 3.02-6.66], cat ((OR) 2.85; 95% (CI) 1.24-6.50), Dermatophagoides farinae (DF) ((OR) 2.41, 95% (CI) 1.65-3.51) and Mixed grass pollen ((OR) 2.85, 95% (CI) 1.24-6.50) were significantly associate with current wheezing atopy ((OR) 1.29, 95% (CI) 0.74-2.24), was not an independent risk factor for current wheezing in children from any of the three cities. Furthermore, atopy ((OR) 2.53, 95% (CI) 1.93-6.97) were significantly associated with BHR. CONCLUSION The authors confirmed that sensitization to house dust mite and cat was significantly associated with current wheezing and bronchial hyperresponsiveness in Chinese schoolchildren
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|a English Abstract
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|a Journal Article
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|a Multicenter Study
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|a Allergens
|2 NLM
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|a Ma, Yu
|e verfasserin
|4 aut
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|a Wang, Hong-yu
|e verfasserin
|4 aut
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|a Wang, Hai-jun
|e verfasserin
|4 aut
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|a Zhao, Jing
|e verfasserin
|4 aut
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|a Cao, Ling
|e verfasserin
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|a Li, Shuo
|e verfasserin
|4 aut
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|a Wong, G W K
|e verfasserin
|4 aut
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|a Zhong, Nan-shan
|e verfasserin
|4 aut
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|a Fok, T F
|e verfasserin
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|a Lai, C K W
|e verfasserin
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|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 41(2003), 7 vom: 27. Juli, Seite 538-41
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|x 0578-1310
|7 nnns
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| 773 |
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|g volume:41
|g year:2003
|g number:7
|g day:27
|g month:07
|g pages:538-41
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|a AR
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|d 41
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