Clinical feature of four cases with bronchiolitis obliterans

OBJECTIVE: To recognize the clinical features of the bronchiolitis obliterans

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 41(2003), 11 vom: 29. Nov., Seite 839-41
1. Verfasser: Liu, Xiu-yun (VerfasserIn)
Weitere Verfasser: Jiang, Zai-fang, Shen, Kun-ling, Zeng, Jin-jin, Xu, Sai-ying
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:Case Reports English Abstract Journal Article
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100 1 |a Liu, Xiu-yun  |e verfasserin  |4 aut 
245 1 0 |a Clinical feature of four cases with bronchiolitis obliterans 
264 1 |c 2003 
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500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To recognize the clinical features of the bronchiolitis obliterans 
520 |a METHOD: Clinical manifestation, chest X-ray, computed tomography (CT) and pulmonary function of 4 cases with bronchiolitis obliterans were retrospectively analyzed 
520 |a RESULT: Two cases were after Stevens-Johnson syndrome (SJS), the other 2 were after severe pneumonia, including one suffered from adenovirus pneumonia. Cough, tachypnea and wheezing persisted in all the 4 patients. The symptoms lasted for at least 6 weeks, in one case for over one year. Crackles and wheezing were present in all the 4 cases. Hyperinflation was seen in chest radiographs in all cases. On pulmonary CT/high-resolution CT (HRCT), patchy opacity and bronchial wall thickening were seen in each patient. Areas of air trapping were seen in three cases. Bronchiectasis was seen in 2 cases, atelectasis and mosaic perfusion were seen respectively in one case. PO(2) was low in all the four cases. Wheezing was not responsive to beta(2) agonist and other bronchodilating therapy. Prednisone was used at a dose of 1 mg/(kg.d) in 3 cases. Two cases were followed up for 3 months. The clinical condition of one case was improved, whose wheezing and bronchiolar constriction disappeared, cough and dyspnea were also relieved. However, the condition of one patient was not improved, although the wheezing disappeared. The HRCT of these two cases showed no improvement 
520 |a CONCLUSION: Clinical symptoms of BO were cough, tachypnea, and wheezing after acute lung injury. Crackles and wheezing were the most common signs in the BO. Chest radiographs showed hyperinflation. Pulmonary CT showed bronchial wall thickening, bronchiectasis, atelectasis, and mosaic perfusion. Pulmonary function tests suggested obstruction of small airway 
650 4 |a Case Reports 
650 4 |a English Abstract 
650 4 |a Journal Article 
700 1 |a Jiang, Zai-fang  |e verfasserin  |4 aut 
700 1 |a Shen, Kun-ling  |e verfasserin  |4 aut 
700 1 |a Zeng, Jin-jin  |e verfasserin  |4 aut 
700 1 |a Xu, Sai-ying  |e verfasserin  |4 aut 
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