Regulation of NF-kappaB/P65 by MDM2 in acute lymphoblastic leukemia in childhood
OBJECTIVE: MDM2 is considered a proto-oncogene due to its ability to inhibit P53 tumor-suppressor function. But, evidence showed that MDM2 might have a P53-independent role in tumorigenesis. MDM2 is over-expressed in human sarcoma and carcinoma. Recent studies showed that MDM2 might act as a transcr...
| Publié dans: | Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 41(2003), 12 vom: 14. Dez., Seite 921-4 |
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| Auteur principal: | |
| Autres auteurs: | , , , , , |
| Format: | Article |
| Langue: | Chinese |
| Publié: |
2003
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| Accès à la collection: | Zhonghua er ke za zhi = Chinese journal of pediatrics |
| Sujets: | Journal Article Research Support, Non-U.S. Gov't Antibiotics, Antineoplastic MAS1 protein, human NF-kappa B Nuclear Proteins Proto-Oncogene Mas Proto-Oncogene Proteins RNA, Messenger Transcription Factor RelA plus... |