Specificity and immunochemical properties of anti-DNA antibodies induced in normal mice by immunization with mammalian DNA with a CpG oligonucleotide as adjuvant
To elucidate the role of DNA antigen drive in the anti-DNA response, the specificity and immunochemical properties of anti-DNA antibodies induced in normal mice by immunization with double stranded (ds) mammalian DNA with a CpG oligonucleotide (ODN) adjuvant were characterized. Like spontaneous anti...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 109(2003), 3 vom: 15. Dez., Seite 278-87 |
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| Format: | Aufsatz |
| Sprache: | English |
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2003
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Adjuvants, Immunologic Antibodies, Antinuclear Antigen-Antibody Complex CPG-oligonucleotide Histones Immunoglobulin Isotypes Nucleosomes mehr... |