Primary research of the effect of intestinal ischemia/reperfusion injury on Leptin concentrations

OBJECTIVE: To explore the effect of intestinal ischemia/reperfusion injury on Leptin concentrations in serum and adipose tissue, and to find out the role of Leptin in acute inflammatory responses

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 15(2003), 12 vom: 15. Dez., Seite 722-5
1. Verfasser: Lin, Ji (VerfasserIn)
Weitere Verfasser: Yan, Guang-tao, Hao, Xiu-hua, Zhang, Kai, Wang, Lu-huan, Xue, Hui
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article Research Support, Non-U.S. Gov't Leptin
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245 1 0 |a Primary research of the effect of intestinal ischemia/reperfusion injury on Leptin concentrations 
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500 |a Citation Status MEDLINE 
520 |a OBJECTIVE: To explore the effect of intestinal ischemia/reperfusion injury on Leptin concentrations in serum and adipose tissue, and to find out the role of Leptin in acute inflammatory responses 
520 |a METHODS: An intestinal ischemia-reperfusion injury model of rats was established, and used a highly-sensitive murine Leptin radioimmunoassay to check the change of Leptin concentrations in serum and adipose tissue 
520 |a RESULTS: Serum Leptin level (10.82+/-0.83) microg/L significantly decreased after an injury of 60-minute ischemia and 30-minute reperfusion versus pre-experimental serum levels (16.46+/-3.21) microg/L; Leptin level in serum was higher than that in adipose tissue (4.466+/-2.63) mg/100g, and they both showed a similar changeable trend to increase step by step as reperfusion time extended (P=0.047) 
520 |a CONCLUSION: Leptin may be an inflammatory cytokine and may play a role in inflammatory responses such as intestinal ischemia/reperfusion 
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650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
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700 1 |a Yan, Guang-tao  |e verfasserin  |4 aut 
700 1 |a Hao, Xiu-hua  |e verfasserin  |4 aut 
700 1 |a Zhang, Kai  |e verfasserin  |4 aut 
700 1 |a Wang, Lu-huan  |e verfasserin  |4 aut 
700 1 |a Xue, Hui  |e verfasserin  |4 aut 
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