B lymphocytes from individuals with common variable immunodeficiency respond to B lymphocyte stimulator (BLyS protein) in vitro

B lymphocytes from individuals with common variable immunodeficiency respond to B lymphocyte stimulator (BLyS protein) in vitro

B lymphocyte stimulator (BLyS protein) is a member of the human TNF family of ligands. BLyS induces B-lymphocyte proliferation and Ig secretion in vitro and in vivo. These qualities suggest that it may be useful as a therapeutic in the treatment of immunodeficiencies characterized by low or absent s...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 109(2003), 2 vom: 15. Nov., Seite 137-43
1. Verfasser: Stewart, Donn M (VerfasserIn)
Weitere Verfasser: McAvoy, Michael J, Hilbert, David M, Nelson, David L
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Adjuvants, Immunologic B-Cell Activating Factor B-Cell Activation Factor Receptor BLyS receptor Immunoglobulin Isotypes Immunoglobulins Membrane Proteins Receptors, Tumor Necrosis Factor Recombinant Proteins mehr... TNFRSF13C protein, human TNFSF13B protein, human Tumor Necrosis Factor-alpha