Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver

Fas Ligand-dependent and -independent mechanisms of toxicity induced by T cell lymphomas in lymphoid organs and in the liver

In the current study, we investigated the effect of growth of FasL(+) tumors in vivo on the functions of peripheral lymphoid organs and the liver. Injection of FasL(+) LSA tumor cells into syngeneic C57BL/6 wild-type mice but not C57BL/6 lpr/lpr (Fas-deficient) mice caused apoptosis in splenocytes....

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 109(2003), 2 vom: 15. Nov., Seite 144-53
1. Verfasser: Lombard, Catherine (VerfasserIn)
Weitere Verfasser: McKallip, Robert J, Hylemon, Philip B, Nagarkatti, Prakash S, Nagarkatti, Mitzi
Format: Aufsatz
Sprache:English
Veröffentlicht: 2003
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Cytokines Fas Ligand Protein Fasl protein, mouse Membrane Glycoproteins Superantigens Aspartate Aminotransferases EC 2.6.1.1